Novel, Fractionated Dosing Formulations for
Optimizing Titration of
Carbidopa/Levodopa
A Practical Roadmap for Improving Patient Satisfaction, Motor Symptoms,
Clinical Outcomes, and ON/OFF Time in Persons with PD
A Practical Roadmap for Improving Patient Satisfaction, Motor Symptoms,
Clinical Outcomes, and ON/OFF Time in Persons with PD
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How do you manage the challenges that accompany the narrowing therapeutic window for CD/LD? Given the evolving therapeutic toolkit—including the availability of fractionated CD/LD dosing formulation—what options go through your mind at this point?
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What new diagnostic modalities—including scans and skin biopsy—are available to support the clinical/motor findings that are characteristic of persons with Parkinson’s Disease?
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How does the neurologist, geriatrician, or movement disorder specialist confirm the diagnosis of Parkinson’s Disease as a prelude or trigger to beginning pharmacologic therapy? What are the pathognomonic features of this disease state?
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Can you provide our neurological and movement disorder specialists with a broad view of critical issues and unmet therapeutic needs for Parkinson’s Disease (PD)?
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Once you are confident with the diagnosis of PD, and you determine that pharmacologic therapy is warranted, what kind of clinical decision tree do you rely on to determine your initial, individualized choice for treatment?
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Can you please provide us with a brief summary of what you plan to cover on today’s CME program and your assessment of unmet needs in the treatment of PD?
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Can you provide some background on the disease burden associated with Parkinson’s Disease, and the challenges of confirming the diagnosis and heterogeneity in clinical presentation?
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Given that CD/LD therapy for PD is highly individualized, what are possible advantages of longer-acting formulations of CD/LD and/or the availability of a scored, fractionable formulation of CD/LD highly amenable to titration by the patient or the physician?
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What are the canonical signs, symptoms and historical features of PD, and what criteria must be met to confirm the diagnosis and consider initiation of pharmacologic therapy?